Can You Use Niacinamide and Retinol Together?

Yes, they work well together

Yes. Niacinamide and retinol are a common, well-tolerated pairing, and you can use them in the same routine. If your skin is new to retinol, start slowly no matter what you pair it with.

How to use niacinamide and retinol in one routine

Morning

Cleanser, niacinamide, moisturizer, sunscreen

Night

Cleanser, retinol, niacinamide or a niacinamide moisturizer

Why

Retinol is a retinoid, the ingredient most likely to cause dryness here. Niacinamide doesn’t exfoliate, so it doesn’t add to that irritation.

You will also find the two combined in many single products, which is an easy way to use them together.

What to watch for

Retinol is the one to watch. Start with two or three nights a week and build up.

Check your whole routine

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  • Niacinamide + Retinol

    Fine together

    Niacinamide is not an exfoliant, so it doesn’t stack irritation. It pairs well with most actives. Read more

A routine that keeps them apart

Morning

Cleanser → Niacinamide → moisturizer → sunscreen

Night

Cleanser → Niacinamide → Retinol → moisturizer

On a prescription? Ask your prescriber before adding other actives. Want this checked against your actual products? Acnera scans your whole routine.

Frequently asked questions

Can You Use Niacinamide and Retinol Together?

Yes. Niacinamide and retinol are a common, well-tolerated pairing, and you can use them in the same routine. If your skin is new to retinol, start slowly no matter what you pair it with.

Should I put niacinamide on before or after retinol?

Either works. Many people apply retinol first and niacinamide after, or use a moisturizer that contains niacinamide.

Can niacinamide reduce retinol irritation?

Some people find it makes retinol easier to tolerate, but the main fix for retinol irritation is starting slowly.

Sources: Shalita et al., Int J Dermatol 1995; AAD: acne skin care tips. General information, not medical advice. If you use a prescription treatment, ask your prescriber before adding actives.

Read the full guide: Skincare ingredients not to mix

Other pairings