Can You Use Glycolic acid and Salicylic acid Together?

Yes, with caution

Yes, but not as two separate strong products layered together. A single product that contains both at low strength is usually fine. Layering a strong glycolic toner over a separate salicylic serum tends to over-exfoliate. Alternate them instead.

How to use glycolic acid and salicylic acid in one routine

Morning

Salicylic acid cleanser on some days

Night

Glycolic acid on other nights, not after salicylic acid

Or use one product that already contains both.

Why

Glycolic acid (an alpha hydroxy acid) loosens dead cells on the surface. Salicylic acid (a beta hydroxy acid) works inside the pore. They are both exfoliants, so their irritation adds up.

The American Academy of Dermatology warns that using too many acne treatments at once can irritate the skin and cause breakouts. Two separate acids in one routine is a common way that happens.

What to watch for

Redness, stinging when you apply moisturizer, and flaking are signs of over-exfoliation. Stop both for a few days, then bring back one.

Check your whole routine

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  • Glycolic / lactic acid (AHA) + Salicylic acid (BHA)

    Use with caution

    Two exfoliating acids. One product with both at low strength is usually fine; layering separate strong ones over-exfoliates. Read more

A routine that keeps them apart

Morning

Cleanser → no actives → moisturizer → sunscreen

Night

Cleanser → Glycolic / lactic acid (AHA) → Salicylic acid (BHA) → moisturizer

Glycolic / lactic acid (AHA) and Salicylic acid (BHA) both land in your night. Use them on alternate days.

On a prescription? Ask your prescriber before adding other actives. Want this checked against your actual products? Acnera scans your whole routine.

Frequently asked questions

Can You Use Glycolic acid and Salicylic acid Together?

Yes, but not as two separate strong products layered together. A single product that contains both at low strength is usually fine. Layering a strong glycolic toner over a separate salicylic serum tends to over-exfoliate. Alternate them instead.

Can I use a glycolic toner and a salicylic serum together?

Not in the same routine. Use them on different nights, or swap to one product that contains both at a lower strength.

Which is better for acne, glycolic or salicylic acid?

Salicylic acid is usually the better pick for clogged pores because it works inside the pore. Glycolic acid works more on the surface.

Sources: AAD: acne skin care tips; FDA: AHA sunburn alert labeling. General information, not medical advice. If you use a prescription treatment, ask your prescriber before adding actives.

Read the full guide: What not to mix with salicylic acid

Other pairings